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How Should I Take ERLEADA®? | ERLEADA® (apalutamide)

How Should I Take ERLEADA®

Prostate cancer patient from ERLEADA® (apalutamide) commercial pouring coffee beans

How should I take ERLEADA®?

Take ERLEADA® as directed by your doctor. The recommended dose of ERLEADA® is 240 mg (four 60 mg tablets) taken orally once daily.


Take ERLEADA® once a day, orally, and with or without food

  • Take ERLEADA® exactly as your healthcare provider tells you.
  • Your healthcare provider may change your dose if needed.
  • Do not stop taking your prescribed dose of ERLEADA® without talking with your healthcare provider first.
  • Take your prescribed dose of ERLEADA® 1 time a day, at the same time each day.
  • Take ERLEADA® with or without food.
  • Swallow ERLEADA® tablets whole.
  • If you miss a dose of ERLEADA®, take your normal dose as soon as possible on the same day. Return to your normal schedule on the following day. You should not take extra tablets to make up the missed dose.
  • You should start or continue a gonadotropin-releasing hormone (GnRH) analog therapy during your treatment with ERLEADA® unless you had a surgery to lower the amount of testosterone in your body (surgical castration).
  • If you take too much ERLEADA®, call your healthcare provider or go to the nearest hospital emergency room.

Unable to swallow tablets whole?

Please read the complete directions for mixing ERLEADA® with applesauce below.

Taking ERLEADA® if you are unable to swallow tablets whole:


1. Place your dose of ERLEADA® in a  container that contains 4 ounces (120 mL) of applesauce and stir. DO NOT crush the tablets.

Stir, wait, repeat

2. Wait 15 minutes and stir the mixture.

3. Wait another 15 minutes and stir the mixture until tablets are well mixed with no chunks remaining.

Swallow mixture

4. Swallow the mixture right away using a spoon.

Rinse, drink, repeat

5. Rinse the container with 2 ounces (60 mL) of water and drink the water mixture right away.

6. Repeat the rinse with 2 ounces (60 mL) of water one more time to make sure that you take your full dose of ERLEADA®.

Swallow all the applesauce and medicine mixture within 1 hour of preparation. DO NOT store ERLEADA® that is mixed with applesauce.



Helpful Information and Resources

Patient and doctor during office visit discussing ERLEADA® (apalutamide)

Doctor Discussion Guide

Contains questions to help start a conversation with your doctor.


Boxing coach with prostate cancer from ERLEADA® (apalutamide) commercial ringside

ERLEADA® Patient Brochure

Contains important information about mCSPC, nmCRPC, and ERLEADA®.